This text comprises paid for content material produced in collaboration with Arvia Expertise.

Energetic Pharmaceutical Substances (APIs) are notoriously tough to take away from wastewater. Conventional water therapy methods don’t simply take away APIs from water, so pharmaceutical firms typically must resort to high-cost incineration as a substitute.

Consumer: International Pharmaceutical Firm

A widely known pharma firm approached Arvia due to the precise situation above. The present disposal answer was incineration however they wished to discover a higher answer which was not as pricey, both financially or to the atmosphere.

Downside: To cut back 4 APIs to PNEC ranges

The pharma big wanted to take away 4 APIs: ibrutinib, topiramate, rilpivirine (TMC278) and paliperidone palmitate. All 4 APIs needed to be diminished to beneath PNEC ranges (Predicted No-Impact Focus). No conventional water therapy methods had been in a position to do that, so the pharma firm had to take a look at new know-how.

Resolution

Arvia Expertise specialises in electrochemical oxidation for removing of persistent natural compounds from industrial wastewater. The vary is named Nyex, and they’re all based mostly on a super-efficient electrochemical oxidation course of, both with or with out an integral adsorption course of in the identical unit.

For this venture, the Nyex Ellenox was chosen. To see how this works, see the beneath brief animation, and for an outline of the product see: https://arviatechnology.com/water-treatment-products/nyex-ellenox/.

Consequence

The PNEC values required for the 4 APIs had been:

• Topiramate 1000μg/L
• Ibrutinib 1.55μg/L
• Ripilvirine 0μg/L
• Paliperidone palmitate 250 μg/L

Nyex Ellenox was proven to take away all 4 APIs to beneath the required PNEC ranges which meant the pharma firm may keep away from the prices of incineration.

Arvia’s CEO, Simon Gatcliffe stated, “Our consumer had budgeted for 1000 tonnes per yr to be incinerated, which equates to about 460,000 Euros. Our answer represents a really robust ROI.”